Askin Rosai Tumour

Malignant small cell tumour (Askin-Rosai) of the pericardium.

An Askin-Rosai tumour presenting as effusive constrictive pericarditis is reported. A 2-D echocardiogram was strongly suggestive of a primary pericardial tumour, and multiple pericardial and pleural aspiration failed to yield malignant cells. The final diagnosis was made at autopsy. Primary pericardial Askin-Rosai tumour has not to our knowledge been previously reported.

Askin tumour: a rare thoracopulmonary tumour in adults.

Askin tumour, a primitive neuroectodermal tumour of the thoracopulmonary region, is a rare tumour presenting in childhood. Its presentation in adults is rare. We report a case of an Askin tumour in an adult patient who presented to us with worsening breathlessness and vague chest pain. Investigations including immunohistochemistry confirmed the diagnosis of Askin tumour.

Abdominal mass and haematuria.

3 Shamberger RC, Grier HE, Weinstein JH, et al. Chest wall tumors in infancy and childhood. Cancer 1989; 63: 774-85. 4 Askin FB, Rosai J, Sibley RK, Dehner LP, McAlister WH. Malignant small cell tumor of the thoracopulmonary region in childhood: a distinctive clinicopathologic entity of uncertain histogenesis. Cancer 1979; 43: 2438-51. 5 Sabate JM, Franquet T, Parellada JM, Monill JM, Olive E. ...

Askin tumor: Case report and literature review

Tumour radiobiology beyond fractionation

Historically it has been shown repeatedly that single high doses of radiation do not allow a therapeutic differential between tumor and critical normal tissues but dose fractionation does. The purpose of conventional dose fractionation is to increase dose to the tumor while preserving normal tissue function. Tumors are generally irradiated with 2Gy dose per fraction delivered daily to a more or...